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Novel mechanism of miRNA processing regulation by autism-related protein MeCP2 (2014/3/11)
Recently, Dr. QIU Zilong’s lab reported that besides transcriptional regulation, MeCP2 could suppress miRNA processing through regulating the DGCR8/Drosha complex.This work was mainly carried out by graduate student CHENG Tianlin and colleagues under the supervision of Dr. QIU Zilong.
Researchers revealed circuit mechanism underlying Drosophila olfactory processing (2014/2/11)
Recently, Dr. WANG Zuoren’s lab found that mlPNs receive inputs from both ORNs and mPNs, and provide lateral outputs to other neurons in the AL via gap junctions. Their study demonstrates that the two pathways formed by GABAergic PNs and cholinergic PNs.
New findings on polarized membrane trafficking for axon development (2014/2/11)
Recently, the research group headed by Dr. LUO Zhenge has shown that Rab10, a member of Rab family of small GTPases, is associated with PPVs, and that Myosin V interaction with Rab10 controls sorting of PPVs from the trans-Golgi network. This study has demonstrated a mechanism underlying directional membrane trafficking involved in axon development.
Oxytocin regulates cortical synaptic transmission during early development (2014/1/27)
On Jan. 26th, Dr. Xiang Yu’s research group at the Institute of Neuroscience, Chinese Academy of Sciences, published a research article entitled "Oxytocin mediates early experience-dependent crossmodal plasticity in sensory cortices" in the journal Nature Neuroscience as Advance Online publication.
New study reveal polarized dendrite formation during adult neurogenesis (2014/1/3)
Recently a study from the Institute of Neuroscience, Shanghai Institutes for Biological Sciences showed that the protein kinase LKB1 regulates polarized dendrite formation of adult hippocampal newborn neurons through asymmetric distribution of Golgi apparatus.These findings provide new clues to the subcellular mechanism of LKB1’s action.
Dr. Xu Zhang was invited to the 5th Asian Pain Symposium in Japan (2014/1/1)
Dr. Xu Zhang was invited to the 5th Asian Pain Symposium in Japan from December 17th to December 21st, 2013. During the symposium, Dr. Zhang gave an invited talk entitled ”Role of FXYD2, γ subunit of Na+,K+-ATPase, in inflammatory pain”.
2013 ION Annual Meeting (2013/12/30)
The 2013 ION Annual Meeting was held at the SIBS Lecture Hall from December 26th to 27th, 2013. Forty-seven ION researchers, including graduate students, postdoctoral fellows and research associates, presented their recent works. New faculty members introduced the research directions of their respective laboratories.
A cumulative mechanism for brain state-dependent fast visual processing (2013/12/23)
Recently, a research team (WANG Xudong, CHEN Cheng, and ZHANG Dinghong) from the laboratory of Dr. YAO Haishan at the Institute of Neuroscience, Shanghai Institutes for Biological Sciences showed that V1 neurons exhibit shorter response latency in the desynchronized brain state than in the synchronized state.
Dr. Jiulin Du gave invited talks at the Institute Pasteur, l'Ecole Normale Supérieure and Curie Institute of France (2013/12/2)
Dr. Jiulin Du was invited to visit the Institute Pasteur, l'Ecole Normale Supérieure and Curie Institute of France during Nov 25 – 30, and gave three talks entitled “Functional crosstalk between resting microglia and neurons”, “Neuronal NMDA receptors regulate brain vascular development” and “A functional module gates visuomotor transformation”.
Revealing the role of Mid1-PP2Ac signaling in axon development (2013/11/19)
Mental retardation is a neurological disorder typically associated with brain malformation and intellectual disability. There is increasing evidence showing that mutations on many X-linked genes can lead to different types of mental retardation. Thus studying their function provides a means to understand the physiology and pathology of the neural system.
Dr. Jia-Wei Zhou was invited to attend the 20th East Asia Joint Symposium in Japan (2013/11/13)
Dr. Jia-Wei Zhou was invited to attend the 20th East Asia Joint Symposium in Japan from November 7th to November 9th , 2013. During the symposium, Dr. Zhou gave an invited talk entitled "Role of dopamine D2 receptor in the control of neuroinflammation".
New molecular mechanism of depression revealed (2013/8/29)
On August 30, 2013, Dr. Hailan Hu’s research group published a research report entitled "βCaMKII in lateral habenula mediates core symptoms of depression" in the journal Science. The authors found the new molecular mechanisms underlying the hyperactivity of habenula in depression and identified new molecular targets for gene therapy of depression.
Dr. Xu Zhang gave an invited talk at International Narcotics Research Conference in Australia (2013/7/22)
Dr. Xu Zhang was invited to attend International Narcotics Research Conference in Australia from July 13th to July 20th, 2013. During the conference, Dr. Zhang gave an invited talk entitled “Opioid receptor trafficking and interaction in nociceptors and its role in opioid tolerance”.
Dr. Xu Zhang gave an invited talk at the 8th International Conference of Neurons and Diseases in Singapore (2013/7/8)
Dr. Xu Zhang was invited to attend the 8th International Conference of Neurons and Diseases in Singapore from July 1st to July 5th, 2013. During the conference, Dr. Zhang gave an invited talk entitled "The function of FGF13 in nerve system".
Mapping the origin of the response properties of single neurons (2013/7/5)
On Jul 1, 2013, Dr. Aike Guo’s research group published a research report online entitled "Transformation of odor selectivity from projection neurons to single mushroom body neurons mapped with dual-color calcium imaging" in the journal PNAS. The authors found a scaling relationship between the average synaptic strength of the PN terminals and the total number of PN terminals a single KC received.
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