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ION Quarterly Report Autumn-Winter 2016
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ION Quarterly Report Spring-Summer 2015
ION Quarterly Report Autumn-Winter 2014
Faculty of the season: Dr. LUO Zhen-ge

Dr. LUO Zhen-ge is the Senior Investigator and Deputy Director of Institute of Neuroscience, Chinese Academy of Sciences. He was trained in molecular biology during his undergraduate study at Nankai University, and in immunology during his PhD in Chinese Academy of Military Medical Sciences. He became interested in neuroscience when he was conducting his postdoctoral training in

Novel lateral amygdala - auditory cortex pathway participates in auditory fear learning

A recent paper published in Nature Neuroscience by researchers from Dr. POO Mu-ming’s lab uncovered a new pathway from the lateral amygdala (LA) to the auditory cortex (ACx) in mice, and found it essential in auditory fear memory retrieval. The LA-ACx pathway undergoes synaptic plasticity days after fear learning, suggesting a role in long-term memory storage. Dual-color in

Origin of mysterious retinal waves

Prior to the maturation of sensory pathways, spontaneous neuronal activities play critical roles in the formation of neural circuits and brain development. In immature retina, patterned spontaneous activities exhibit wave-like propagation among neighbouring retinal ganglion cells (RGCs), called retinal waves. However, the origin and underlying mechanism of retinal waves, especially the ones

TMC regulates Drosophila larval locomotion

Mechanosensations, including touch, hearing, proprioception, and mechanical nociception, are essential for animals to regulate their behaviors. Locomotion requires peripheral sensory feedback from mechanosensitive proprioceptors. Thus, mechanosensation is also critical to animals’ Locomotion.

Autophagy induction promotes axon regeneration after spinal cord injury

The limited intrinsic axon growth capacity, the presence of extracellular inhibitory factors, and the lack of neurotrophic factors are major obstacles limiting regeneration of CNS axons after injury. However, manipulating individual proteins or combinations only allows limited axonal regeneration or sprouting and is usually associated with just temporary improvement in functional recovery.

Expression of a hominoid-specific gene induces cortical folding in mice

The outer layer of the mammalian brain, the cerebral cortex, plays a key role in memory, attention, awareness and thought. While rodents have a smooth cortical surface, the cortex of larger mammals such as primates is organized into folds and furrows. These folds increase the amount of cortex that can fit inside the confines of the skull, and are thought to allow the evolution of more advanced cognitive processes.

Network communication predicts perceptual variability in visual illusion
A recent study published in Cerebral Cortex demonstrated that dynamic network communication in human visual cortex predicted perceptual variability of Pinna illusion. This work was performed by researchers in Dr. WANG Zheng’s lab, in close collaboration with Dr. GU Yong and Dr. WANG Wei at the Institute of Neuroscience, Chinese Academy of Sciences.
Dynamic changes of human connectomics for inherent functional flexibility

On Sept. 28, the Journal of Neuroscience online published an article entitled “Dissociable Changes of Frontal and Parietal Cortices in Inherent Functional Flexibility across the Human Life Span” contributed by Laboratory of Brain Imaging, Institute of Neuroscience, Chinese Academy of Sciences. Using a Shannon entropy-based method, this paper unraveled dynamic changes of brain

Neuronal activities in Periaqueductal gray underlie

Defensive behaviors (e.g. flight, freezing and risk assessment)is essential for animals’ survival in nature. Previous studies have suggested that the midbrain periaqueductal gray (PAG) participates in the control of defensive behaviors. However, few studies have examined the neurophysiological mechanism of PAG underlying defense.

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